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Fexofenadine is an antihistamine medication used to treat allergic symptoms. It is commonly employed to alleviate symptoms such as sneezing, runny nose, itching, and watery eyes associated with conditions like hay fever or allergic rhinitis. Fexofenadine works by blocking the effects of histamine, a natural substance in the body that contributes to allergy symptoms. Although it can cause sedation, generally this medication is known for its non-drowsy formula, making it a preferred choice for many individuals who want relief from allergies.

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Fexofenadine is an antihistamine, a class of medications that counteract the effects of histamine in the body. Histamine is a chemical released during allergic reactions and contributes to symptoms such as sneezing, itching, watery eyes, and runny nose. Fexofenadine is commonly used to treat allergic conditions, including seasonal allergic rhinitis (hay fever) and chronic idiopathic urticaria (hives without a known cause).

Key points about fexofenadine:

Mechanism of Action:

  • Fexofenadine selectively antagonizes the H1 receptors, which are histamine receptors found in various tissues throughout the body.
  • By blocking these receptors, fexofenadine prevents the effects of histamine and alleviates allergy symptoms.


  • Fexofenadine is well-absorbed after oral administration and reaches peak plasma concentrations within 1-3 hours.
  • It undergoes minimal metabolism in the liver, primarily through intestinal mucosal cell enzyme metabolism.
  • The drug is excreted largely unchanged in the feces and urine.




  • Fexofenadine may interact with certain medications, so it's essential to inform healthcare providers about all drugs, supplements, and herbal products being used.

It's crucial for individuals to follow their healthcare provider's guidance and read the medication label for specific instructions. If any unusual or severe side effects occur, medical attention should be sought promptly. As with any medication, fexofenadine should be used under the supervision and recommendation of a qualified healthcare professional.



The recommended dose of fexofenadine hydrochloride for adults is 120 mg once daily taken before a meal. Fexofenadine is a pharmacologically active metabolite of terfenadine.

Paediatric population

▪ Children aged 12 years and over

The recommended dose of fexofenadine hydrochloride for children aged 12 years and over is 120 mg once daily taken before a meal.

▪ Children under 12 years

We do not sell this for children under 12, please see you you GP.



  • The typical dose for adults is 120mg once daily.
  • The drug is often taken with water and can be taken with or without food.

Special Considerations:

  • Fexofenadine is known for its non-sedating properties, making it a preferred choice for individuals who want relief from allergy symptoms without experiencing drowsiness, However some people may still get sedation therefore we recommend caution when taking this medicine and to read the patient information leaflet carefully.
  • It is generally considered safe for use in adults and children over the age of 12.

Side Effects:

  • Common side effects include headache, back pain, cough, and fatigue.
  • Serious side effects are rare but may include allergic reactions, such as rash, itching, swelling, severe dizziness, or difficulty breathing. If you experiance any of these stop taking the medicine immediately and seek urgent medical advice.